Bioinformatics is an interdisciplinary field that takes on the challenge of analyzing, visualizing, and interpreting large-scale biological data with the help of high-powered computing to advance our knowledge in multiple disciplines ranging from molecular genetics to precision medicine and cancer. Responding to this need, the San Antonio Life Sciences Institute (SALSI) has funded summer…, Jamie Benavides, is pursuing a B.S. in biochemistry and neurobiology. He will be working with UT Health San Antonio Ashbel Smith tenured professor of biochemistry and structural biology,, Jean Jiang, Ph.D., to learn about the role of cell signaling through hemichannels in bone cells. Jamie aspires to be a neurological surgeon with a research interest in how protein synthesis affects cancer cells. Dr. Jiang will be the perfect mentor to guide Jamie through his career development. , Wala Elsharif, is pursuing a M.S. in computer science and is fluent in several programming languages. Previously, she was involved in a research project to develop algorithms predicting mental illness among workers in technology fields. She will be working with UT Health San Antonio assistant professor and CPRIT scholar,, Jason Liu, Ph.D., , focusing on the epigenetic architectures of cancers that resist hormone treatments. The aim of this project is to identify potential therapeutic targets that mitigate tumor development. Wala’s career goal is to learn more about machine learning in the healthcare field. , Aaron Ferrer, is pursuing a B.S. in computer engineering and is proficient in several programming languages, including Python and Matlab. Passionate about artificial intelligence (AI), he will be working with UT Health San Antonio professor and director of computational biology at the Greehey Children’s Cancer Research Institute,, Yidong Chen, Ph.D., The team will train a deep learning (DL) machine to predict the drug response of FDA-approved cancer treatments using genomic data. Further, Aaron and Dr. Chen will compare this DL method to other conventional machine learning tasks. His future goal is to learn how to use AI in agriculture to help tackle issues surrounding food security. Strong mentorship leads to big success Two of the key…
Proof of concept is a significant milestone in de-risking an idea and attracting additional research development investment. Since 2015, the President’s Translational and Entrepreneurial Research Fund (PTEF) has been supporting bioscience innovation with early-stage seed funds for projects that have a high probability of being commercialized, but are unlikely to succeed without gap funding. The…, Charlotte Anthony, , B.A. marketing specialist senior in the Graduate School of Biomedical Sciences, is the visionary creator of, Pipette Kids Science Education Materials for Kids, to engage and introduce K-12 students to STEM related careers and topics in various enjoyable interactive ways. Ms. Anthony will seek to further commercialize her portfolio with a start-up company to meet the growing demand for education materials targeting kids. , Maria Gaczynska, , Ph.D., associate professor, and, Pawel Osmulski, , Ph.D., assistant professor, department of molecular medicine jointly proposed how to specifically kill cancer cells in solid cancers, metastasis of solid cancers, and drug-resistant blood cancers via proteasome inhibitors. These, inhibitors may have reduced toxicity, increase life expectancy and improve quality of life, . , Randolph Glickman, , Ph.D. professor of ophthalmology and, Saher Maswadi, , Ph.D., professor of physics and astronomy at UTSA, (and former postdoctoral fellow in Dr. Glickman’s lab) presented their EchoLase Imaging System. This system is based on a probe beam deflection technology (PBDT), which is, a laser-based high definition medical ultrasound device offering higher quality imaging at lower costs, than medical ultrasound technology currently in use., Cara Gonzales, , D.D.S., Ph.D., '03 associate professor of comprehensive dentistry, proposed a novel capsazepine analog to treat oral cancer. Head and neck cancer is the sixth most common cancer globally. If successful in development, this compound would be the first new effective therapy developed in 50 years. Funds were requested to complete toxicity studies in vivo. , James Lechleiter, , Ph.D., professor of cell systems and anatomy, pitched his research on neurodegenerative diseases. He co-founded a drug company based in Cambridge, M.A., Astrocyte Pharmaceuticals , which is focused on, breakthrough therapeutic agents for treating Traumatic Brain Injury, as well as other chronic neurodegenerative disorders, ., Luiz F. Maracaja, , M.D., assistant professor of anesthesiology, presented the Line Guard, an, improved design for stopcocks used for drainage on catheter tubing, that reduce the chances of contamination, infection, mal-positioning, and medication errors. Developed with an array of different product solutions, Dr. Maracaja is building on his PTEF 2016 award to further his commercialization milestones., Robert Mora, , M.D., assistant professor of emergency medicine, pitched the Pulse-Strip, an, adhesive strip with sensors to detect and monitor a patient’s pulse, accurately and continuously during a potentially fatal 'code' event. Funds were requested for the development of a prototype. , Ahmed Sabbah, , D.D.S., Ph.D., clinical assistant professor of comprehensive dentistry, developed a novel software, application (with mobile device integration) for clinical grading in dental school clinics that would reduce errors, , streamline grading, and provide better feedback., Michael Schwirian, , database analyst, and, Carl Middleton, , program analyst, from the department of neurosurgery jointly, developed a medical residency assessment tool (, RATE, ) designed to manage and ultimately match the best medical school candidates into residency programs, across the country., Steven G. Venticinque, , M.D., interim chair, department of anesthesiology,, developed an improved airway management intubation device,, Smarter Stylets ,, that surpasses currently available devices for speed, ease of use, reduced complications and autonomy, .