In a new paper, researchers from UT Health San Antonio report brain chemistry that may contribute to why drinkers have difficulty paying attention while under the influence. The work is funded by generous support from the Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation and by grants from the National Institute on Alcohol Abuse and Alcoholism and the National Institute of Mental Health.…, Martin Paukert, MD, , assistant professor of cellular and integrative physiology at UT Health San Antonio. When attention is needed for a task, norepinephrine is secreted by a brain structure called the locus coeruleus. Scientists previously did not understand well what happens next, but Dr. Paukert and the team showed that the norepinephrine attaches to receptors on cells called Bergmann glia. This leads to a…, Ethanol abolishes vigilance-dependent astroglia network activation in mice by inhibiting norepinephrine release, Liang Ye, Murat Orynbayev, Xiangyu Zhu, Eunice Y. Lim, Ram R. Dereddi, Amit Agarwal, Dwight E. Bergles, Manzoor A. Bhat and Martin Paukert First published: Dec. 2, 2020, Nature Communications https://doi.org/10.1038/s41467-020-19475-5