Long School of Medicine

The Future of Vaccines: An Interview with the Doctor Who Created the First Fully Humanized Immune Systems in Mice

FACULTY:
Paolo Casali, MD the University of Texas Ashwell Smith Professor and Distinguished Research Professor of Microbiology, Immunology, and Molecular Genetics. 

OVERVIEW:
Dr. Casali and his team have achieved a groundbreaking milestone by creating the first fully humanized immune system in mice. This episode delves into the significance of this achievement, exploring its potential impact on vaccine development, medical research, and therapeutic treatments. Dr. Casali explains the intricate process of developing these humanized mice, the role of human hematopoietic stem cells, and the crucial importance of hormonal conditioning with estrogen. The conversation also touches on the ethical implications and future possibilities of this innovative research.

OVERALL LEARNING OBJECTIVE:
Increased awareness and education for pediatric providers

DISCLOSURE TO LEARNERS:
Paolo Casali, MD, has no financial relationships with ineligible companies to disclose.

The Pediatric Grand Rounds Planning Committee (Deepak Kamat, MD, PhD, Steven Seidner, MD, Daniel Ranch, MD and Elizabeth Hanson, MD) has no financial relationships with ineligible companies to disclose.

The UT Health Science Center San Antonio and Deepak Kamat, MD course director and content reviewer for the activity, have reviewed all financial disclosure information for all speakers, facilitators, and planning committee members; and determined and resolved all conflicts of interests.

CONTINUING MEDICAL EDUCATION STATEMENTS:
The UT Health Science Center San Antonio is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The UT Health Science Center San Antonio designates this live activity up to a maximum of 0.75 AMA PRA Category 1 Credits.

Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CERTIFICATE OF ATTENDANCE:
Healthcare professionals will receive a certificate of attendance and are asked to consult with their licensing board for information on applicability and acceptance.

Credit may be obtained upon successful completion of the activity’s evaluation.

RELEASE DATE:
8/23/2024 

EXPIRATION DATE:
8/31/2026