Targeting brain immune cells could restore Alzheimer’s-related lipid imbalance

  More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as “lipoid granules,” along with the buildup of amyloid-beta (amyloid) plaques and tau protein tangles. These observations led to the identification of Alzheimer’s disease and related dementias. Since then, most Alzheimer’s research has focused on amyloid and tau, […]