March 17, 2000
Volume XXXIII, No. 11
When Dr. Wen-Hwa Lee left his laboratory in Southern California almost 10 years ago to travel to the brand-new Hayden Head Building at the Health Science Center's Institute of Biotechnology (IBT), his mission was clear--build a world-class research facility in the brushland of South Texas.
The IBT, located in the Texas Research Park 20 miles west of San Antonio, was surrounded by only wildflowers and mesquite trees. Dr. Lee took up the challenge and a decade later the institute continues to grow in size and reputation, drawing top scientists to its ranks and offering a world-class graduate program in molecular medicine.
"It has been a very exciting time for us," said Dr. Lee, director of the IBT, who arrived in San Antonio in July 1991 with his researcher wife, Dr. Eva Lee, and a team of 20 investigators. "We have achieved a great deal over the years and the future of this park is very bright and exciting."
What began as a team of 30 scientists in a largely vacant building has grown into a group of 110 researchers in four sets of laboratories conducting investigations in molecular medicine that may one day lead the way to treatments for a host of diseases.
"It has been tremendously satisfying to go from nothing to what is here now and to see the potential for the future," said Dr. Z. Dave Sharp, deputy director of the IBT, who moved his laboratories and team of five researchers to the building in 1990 to prepare for Dr. Lee's arrival. "It is an environment that fosters good critical leading-edge science."
Leading-edge science is just what Dr. Lee had in mind when he moved his laboratories to Texas almost a decade ago. Dr. Lee was a pioneering cancer geneticist when he took the reins to lead the IBT, having already led research that found the first human gene linked to the causes of cancer. He continues his own research on a cancer tumor suppressor gene, while at the same time recruiting new scientists and educating future researchers.
"I have learned a lot in the last nine years," said Dr. Lee. "It is a challenge. You have a mission to accomplish, and either you do it or you fail. I succeed because my staff shares the same vision I do. They share my optimism and therefore we can make it."
The institute's staff and reputation have grown as grants for research projects have increased. Funding from the National Institutes of Health nearly quadrupled from $6 million in the institution's fledgling years to $23 million in 1999. Many of the IBT's scientists and their projects have been featured in national and international journals, including the prestigious journal Nature.
Along with its research reputation, the institute has built a thriving graduate program in molecular medicine. Since its inception in 1993, initial student enrollment has more than doubled, making molecular medicine the largest graduate program at the Health Science Center.
Additional accomplishments include the institute's seminar series, started in 1991, that has drawn noteworthy speakers on genetics and molecular medicine from such prestigious institutions as Harvard, Johns Hopkins, Princeton and Stanford.
Dr. Lee continues to look to the future, hoping to increase graduate student enrollment and to add more researchers to the IBT staff. He predicts that the institute will be an integral part of the "science city" complex envisioned for the Texas Research Park. A second Health Science Center building--the $19 million South Texas Centers for Biology in Medicine--is nearing completion at the park, and several other buildings are in the planning stages.
"It is a great opportunity for us to build a critical mass of scientists in this research park," said Dr. Lee. "Only as we work together will we be able to build a truly outstanding biotechnology center in San Antonio."
Zachary Mackey's interest in science began at age 7 when he was watching an uncle mix household chemicals for a school science experiment. The chemicals combusted and produced an unexpected small explosion that also ignited Mackey's love of science that day.
Preparing to become a scientist is never easy and it was even less so for Mackey. The Southeast Side native was an avid athlete at Highlands High School and then at The University of Nebraska, where he played football and lettered in track. But academically he was less successful--graduating from Nebraska with a less-than-stellar grade point average.
Returning to San Antonio, Mackey worked at a virus reference laboratory and took refresher classes in basic science at The University of Texas at San Antonio, hoping to eventually attend graduate school and pursue his dreams of scientific research.
Shortly after he finished the refresher courses, Mackey was hired as a research assistant at the Health Science Center's Institute of Biotechnology (IBT) in the laboratory of Dr. Barbara Christy, assistant professor in the Department of Molecular Medicine. Working with Dr. Christy provided Mackey with hands-on experience in basic science research and the molecular biology techniques he would need to move forward in the field.
"Just by chance, the IBT was starting its molecular medicine graduate program at that time. I wanted to give graduate school a try because, although I liked the work I was doing, I wanted to advance to a higher level," Mackey said. "I didn't want to remain a research assistant. I wanted to be the researcher."
Getting accepted to the IBT's program was not easy. Without a high grade point average and extensive scientific background, Mackey had to be quite persuasive, but his determination was evident to Dr. Z. Dave Sharp, associate professor who was the assistant director and graduate adviser for the fledgling graduate program at the time.
"I still didn't give up," said Mackey. "I knew I could do it, so I stayed around the lab and watched what everyone was doing--what the students were studying. I stayed at the lab later and later and I learned everything I could and what it was going to take to succeed as a graduate student. Then I applied to the program and prayed and prayed."
In the fall of 1993, Mackey was accepted. He followed with doctoral research work at the IBT in the DNA repair field, studying mammalian DNA ligases with Dr. Alan Tomkinson, associate professor in the Department of Molecular Medicine. In 1997 Mackey was awarded the Howard Hughes Foundation Grant for Minorities in Science totaling $22,250, and the Merck/United Negro College Fund Grant for $25,000, with an additional $15,000 for supplies to continue his research work. He has authored seven publications in peer-reviewed scientific journals, including two first author publications and one review article.
In February, Mackey became Dr. Mackey, receiving his Ph.D. in Molecular Medicine.
"The faculty members at the IBT have given me the opportunity of a lifetime," said Dr. Mackey. "The facility here is unmatched. I knew this was what I wanted and I never gave up. You have to be persistent and if there is a barrier in the way, you have to go around it or move it."
Dr. Mackey is heading for a postdoctoral fellowship at The
University of California, San Francisco, and will do research work on
Bartter Scholar Program taking applications
The Frederic C. Bartter General Clinical Research Center is taking applications for its 2000 scholar program--a six-to eight-week clinical research rotation with a stipend of $800 a month for a Health Science Center student.
Applicants should submit a three-page study proposal. Applications should include a letter of support from a faculty mentor and a brief letter from the student outlining the project's purpose. The deadline for proposal submissions is April 1. For more information, contact Dr. Michael Lichtenstein at ext. 7-4629.
Aging Research and Education Center offers pilot grant program
The Aging Research and Education Center (AREC) is seeking pilot grant proposals in gerontology from Health Science Center faculty.
Grants of up to $40,000, renewable for a second year, will be awarded through the Nathan Shock Center and AREC. Preferential consideration will be given to junior faculty beginning research careers and established investigators who are new to gerontology and geriatrics. Grant proposals also will be considered for projects examining novel ideas that are meritorious but lack sufficient development to compete for extramural funding. Investigators competing in this category may be faculty at any level, including those experienced in aging research.
Applications are due April 14. Proposals must include specific aims of research, a brief background section, description of research methods, a discussion of how the pilot grant will help leverage additional extramural funding, a budget and justification, a two-page biosketch and a list of other funding support being used.
Dr. J. Randy Strong, pharmacology, is heading the AREC pilot grant program. To reach Dr. Strong or for more information, contact Norma Lundberg at ext. 7-2568.
The following new and competitive renewal grants and awards were recorded in the Office of Grants Management for January 2000.
"Scarce Medical Specialist Service Contract for Anesthesiology Services," Dr. Joseph Naples, Veterans Administration (VA), $1,046,064, 1 year.
Cellular & Structural Biology
"Intergovernmental Personnel Agreement (IPA) for Annalise Castro," Dr. Bandana Chatterjee, VA, $23,980, 1 year.
"Tissue Engineering of Oral Tissues," Dr. Robert Klebe, Kalgen Inc., $5,500, 1 month.
"Prevention of Estrogen-Induced DNA Damage & Cancer with Melatonin," Dr. Russel Reiter, Amoun Pharmaceutical Industries Co., $380,472, 1 year.
Emergency Medical Technology
"San Antonio Emergency Medical Services (EMS)," Dr. Donald Gordon, City of San Antonio, $2,190,584, 1 year.
"Strengthening HIV/AIDS & STD Prevention Through Use of Behavioral Data in Programmatic Decision Making," Dr. Alfonso Holguin, Texas Department of Health, $91,977, 1 year.
"Procurement of Health Promotion, Prevention & Training Activities," Dr. Joshua Freeman, Bexar County, $162,150, 1 year.
"Salary Reimbursement Agreement--Corpus Christi," Dr. Joshua Freeman, Christus/SPOHN Memorial Medical Center, $2,251,828, 1 year.
Institute of Biotechnology
"Training Program in the Molecular Basis of Breast Cancer Research," Dr. Wen-Hwa Lee, U. S. Army Medical Research & Materiel Command, $800,000, 1 year.
"The Roles of DNA Ligase I in Mammalian DNA Metabolism," Dr. Alan Tomkinson, National Institutes of Health (NIH)/National Institute of General Medical Sciences (NIGMS), $729,335, 1 year.
"IPA for Annie Almanza," Dr. Cynthia Mulrow, Biomedical Research Foundation of South Texas, $14,756, 9 months.
"Hematology Professional Services," Dr. David Boldt, VA, $52,456, 1 year.
"Cancer Therapy & Research Center (CTRC) Clinical Fellow: Dr. Dina Tebcherany," Dr. Geoffrey Weiss, CTRC Research Foundation, $47,861, 1 year.
"CTRC/Southwest Oncology Group (SWOG) Interim Executive Officer," Dr. Peter Ravdin, CTRC Research Foundation, $92,161, 1 year.
"New Approaches to Brain Tumor Therapy," Dr. Pamela New, Johns Hopkins University, $54,384, 1 year.
"New Approaches to Brain Tumor Therapy," Dr. Pamela New, Johns Hopkins University, $3,000, 1 year.
"IPA for Weiguo Zhao," Dr. Peter Melby, South Texas Veterans Health Care System (STVHCS), $36,508, 1 year.
"The Role of Calreticulin in Cardiac Development & Pathophysiology," Dr. Senlin Li, American Heart Association, $260,000, 1 year.
"IPA for Dr. Narayanasamy Elango," Dr. Michael Katz, STVHCS, $66,394, 1 year.
"1999 Biomedical Research Support Program for Medical Schools," Dr. Robert Clark, Howard Hughes Medical Institute, $1,600,000, 1 year.
"Service Agreement--Karen Davidson as Research Scientist," Dr. Geoffrey Weiss, CTRC Research Foundation, $52,559, 1 year.
"Specialized Center of Research in Scleroderma," Dr. Michael Fischbach, U. T. Health Science Center at Houston, $44,841, 1 year.
"Choroidal Autoregulation & Ocular Pressure Homeostasis," Dr. Jeffrey Kiel, NIH/National Eye Institute (NEI), $703,827, 1 year.
"Role of Bone Factors in Endochondral Ossification," Dr. Barbara Boyan, NIH/National Institute of Dental & Craniofacial Research (NIDCR), $262,455, 6 months.
Otolaryngology–Head & Neck Surgery
"Development of Vestibular Organs in Microgravity," Dr. Michael Weiderhold, NASA, $34,656, 3 months.
"ABT-773 Study Agreement," Dr. James Jorgensen, Abbott Laboratories, $12,000, 1 year.
"Reference Laboratory for Streptococcus Pneumoniae Antimicrobial Resistance," Dr. James Jorgensen, $111,600, 1 year.
"In Vitro Assessment of the Activity of Cefditoren Against Selected Pathogens," Dr. James Jorgensen, TAP Holdings Inc., $3,000, 6 months.
"Addressing Sentencing-Related Changes in Correctional Health Care: Building a Research Practitioner Partnership," Dr. Jacques Baillargeon, Department of Justice, $140,924, 1 year.
"Research Products with General & Specific Applicability to the Product Emdogain," Dr. David Cochran, Biora, $275,000, 1 year.
"Non-Human Primate Studies of Oral Disease," Dr. Jeffrey Ebersole, Procter & Gamble, $68,276, 5 months.
"Involvement of Genomic Instability in Atherosclerosis," Dr. Zhongmao Guo, American Heart Association, $255,273, 1 year.
"The Effect of Nystatin-Impregnated Tissue Conditioner on Candida-Associated Denture Stomatitis," Dr. Kelley Tomsett, American College of Prosthodontists, $5,000, 4 months.
"Provision of Child & Adolescent Psychiatry Services to the Juvenile Probation Unit," Dr. Charles Bowden, Texas Department of Mental Health & Mental Retardation (MHMR)/Center for Health Care Services, $9,750, 2 months.
"Children's Medication Algorithm Project: A Pilot Study," Dr. Steven Pliszka, MHMR, $16,625, 1 year.
"Southwest Mental Health Center," Dr. Charles Bowden, Southwest Neuropsychiatric Institute, $49,157, 1 year.
"Schizophrenia Module of the Texas Medication Algorithm Project," Dr. Alexander Miller, MHMR, $99,568, 1 year.
"National Cancer Institute Subgrant with American College of Radiology," Dr. Gerald Dodd, American College of Radiology Imaging Network, $3,000, 9 months.
"Scarce Medical Specialist Services--Medical Physicist," Dr. Stewart Reuter, VA, $80,703, 1 year.
Research Imaging Center
"Chinese Language Studies Using fMRI Techniques," Dr. Jia-Hong Gao, University of Hong Kong, $50,000, 1 year.
"Role of TGF Beta Receptors & Tumor Progression," Dr. Luzhe Sun, NIH/National Cancer Institute (NCI), $337,374, 1 year.
"Urologic Cancer Outreach ProgramSWOG & CTRC," Dr. Joseph Basler, CTRC Research Foundation, $7,514, 1 year.
"Autocrine Function & Control in Colon Cancer," Dr. Michael Brattain, NIH/NCI, $1,134,025, 1 year.
"Clinical Transplant Coordinator to VAMC," Dr. Glenn Halff, VA, $7,567, 2 months.
"Clinical Transplant Coordination to VAMC," Dr. Glenn Halff, VA, $31,178, 1 year.
"Influence of DNA Nucleotide Mismatch Repair Mutations on Tumor Susceptibility to MGI 114," Dr. Alexander Miller, CTRC Research Foundation, $12,000, 1 year.
Brain cancer patients now have access to an innovative treatment that places a high dose of radiation directly into suspect tissue--areas most likely to contain residual cancer cells after tumor removal.
Clinical trials are beginning at the Health Science Center, one of five medical centers to test the GliaSiteTM Radiation Therapy System (RTS) developed by Proxima Therapeutics. The studies are being conducted under the guidance of the National Cancer Institute's "New Approaches to Brain Tumor Therapy" (NABTT) program.
"The procedure may improve the therapeutic outcome for adults with malignant brain tumors," said Dr. Pamela New, assistant professor of medicine, the Health Science Center's lead investigator on the project. "During this multicenter clinical study as an NABTT member, we will continue our mission to conduct clinical evaluations of promising new treatment strategies for central nervous system malignancies."
The device is a reservoir implanted during surgery to remove a brain tumor. Soon after surgery, the reservoir is filled with liquid radiation that will disable stray cancer cells. The device is removed within three days to a week, and treatment is complete.
The procedure has the potential to improve quality of life for patients. Advantages over traditional therapies may include:
delivery of site-specific, internal radiation that limits exposure to healthy brain tissue;
the opportunity to avoid side effects associated with chemotherapy; and
cost that is 25 percent to 50 percent less than conventional therapies.
The American Cancer Society estimates that about 18,000 U.S. patients are diagnosed each year with malignant brain tumors, and nearly all experience tumor recurrence after initial treatment. Most tumors recur within a short period of time and more than 80 percent are located within two centimeters of the original cancer site.
The traditional treatment for malignant brain tumors is to apply external beam therapy after surgery. Radiation therapy destroys tumor tissue that cannot be surgically removed or is used after surgery to kill remaining cancer cells. Treatment depends on numerous factors, including the type, location and size of the tumor, as well as the patient's age and general health.
With conventional external beam therapy, the radiation travels from the outside in, passing through healthy brain tissue first. While radiation is proven to suppress tumor recurrence, a second course of external beam treatment is rarely an option due to the unacceptable risk to healthy tissue. Treatment for recurrent tumors has been limited.
The experimental treatment combines a balloon catheter with a liquid radiation medication developed to treat patients with malignant brain tumors. During surgery, a neurosurgeon positions the balloon portion of the GliaSite catheter into the cavity created after the malignant brain tumor is removed.
The other end of the catheter extends to the outside of the skull and is concealed underneath the skin at the top of the head.
When the patient recovers from surgery, the liquid solution is injected into the catheter and fills the balloon. After delivering a specified dose of radiation for three to seven days, the solution is withdrawn and the balloon catheter is removed during a brief surgical procedure.
Studies have demonstrated that survival for patients with recurrent malignant brain tumors is approximately three months without therapeutic measures, five months with surgery alone, eight months with surgery and chemotherapy, and 15 months with surgery and internal radiation.
"While it is possible to deliver additional radiation via seed implants--a process known as brachytherapy--the complexity and complications associated with this procedure have limited physicians' use of the therapy," Dr. New said. "The GliaSite RTS is designed to overcome these obstacles so that the value of internal radiation can be made widely available to malignant brain tumor patients."
Up to 40 patients will participate in the GliaSite RTS clinical trials. All must have a recurrent, malignant brain tumor and a history of prior treatment including surgery, radiation therapy and possibly chemotherapy. The study is expected to be complete by year's end, and Proxima is seeking U.S. Food and Drug Administration approval to market the device.
The five U.S. academic medical facilities participating in the GliaSite RTS clinical study are members of the National Cancer Institute-funded NABTT Brain Tumor Consortium. The four other institutions are the Johns Hopkins University School of Medicine (Baltimore), the Wake Forest University School of Medicine (Winston-Salem, N.C.), the Emory University School of Medicine (Atlanta) and Henry Ford Hospital (Detroit).
Kimatha Oxford, assistant professor in the Department of Occupational Therapy, had an article published in a recent issue of the Journal of Hand Therapy. The article, "Elbow Positioning for Maximum Grip Performance," clarified discrepancies in how to best position the elbow to measure grip strength. Oxford found that grip strength is significantly greater when measured with elbows fully extended.
Dr. Michael Wiederhold, otolaryngology-head and neck surgery, was elected to the Board of Directors of the American Society for Gravitational and Space Biology at the 15th Annual American Society for Gravitational and Space Biology Meeting held in Seattle.
As a doctoral student at the Health Science Center, and now as assistant professor in the Department of Family Nursing Care, Dr. Jeanne Ruiz has focused on a specific question: How can women at risk for delivering early be identified before it is too late? So far, Dr. Ruiz knows this for certain--stress is linked to poor birth outcomes.
In a study recently completed, Dr. Ruiz and colleagues measured the perceived stress in a group of 78 pregnant women using a standardized scale. Women who indicated stress were more likely to deliver prematurely. Dr. Ruiz also found that reducing a mother's stress between 24 and 32 weeks' gestation can improve gestational age.
"Assessing a woman's lifestyle has not been a big focus of prenatal care," she said. "What ongoing conditions are affecting her? Does she have help at home? We are not identifying these women soon enough. We need something objective to measure a woman's stress level that we can use in clinical practice."
Stress plays a part in other traditional markers for prematurity, such as smoking, small stature, infection, youth, low socioeconomic level and an unstable environment. Dr. Ruiz is active in the teen smoking cessation project headed by Dr. Kathleen Stevens at University Hospital, where many of these stress factors are evident in patients.
"The goal is to set up a program for everybody and try non-medical interventions, such as counseling, screening for infections, monitoring weight gain and encouraging rest. We don't want to wait until they have to be rushed to the hospital to stop early contractions."
While earning her doctoral degree, Dr. Ruiz initiated an intervention program in an Austin clinic with mothers of twins, a traditional indicator of premature birth. Through a series of weekly visits, the women were screened for infection, weighed and counseled, with very positive results. Dr. Ruiz would like to duplicate those efforts in San Antonio.
Dr. Ruiz is working on biological screening tools to target patients who are at risk for delivering early. A substance related to stress response, called corticotropin releasing factor, and the hormone AFP (alpha-fetoprotein) can be early markers. She is developing a technique to measure threshold levels of these factors in Mexican-American women. The study will last about a year and a half and measure at least 500 women. Dr. Ruiz is hopeful this will lead to future studies and public health interventions.
Dr. Ruiz graduated from The University of Texas at Austin and earned her master's degree at the U.T. Southwestern Medical Center in Dallas. She is a clinical nurse specialist in perinatal care as well as a women's health nurse practitioner and has practiced in a number of settings. She received her Ph.D. from the Health Science Center last year.
Inquisitive South Texans of all ages are invited to get a rare glimpse of the biosciences during the first night of the 2000 Mini-Medical School to be offered throughout April at the Health Science Center. This four-week course, free to the public, will be offered Tuesdays from April 4 to April 25.
The first evening includes breakout sessions with hands-on activities in the fields of medicine, dentistry, nursing, research and emergency medical technology. Subsequent evenings will focus on the heart, the brain and living with illness.
Each Tuesday's program starts at 7 p.m. in lecture hall 3.102B next to the Health Science Center's Dolph Briscoe, Jr., Library. The public is invited to any or all of the four sessions, but early registration is encouraged due to limited seating capacity. To register, call 7-1925 as soon as possible or access the Health Science Center's Mini-Medical School Web page at http://minimedschool00.uthscsa.edu.
The Mini-Medical School brings together presenters from the Health Science Center's Medical, Nursing, Dental, Allied Health and Graduate Schools. The first session, "Exploring the Health Sciences: An Evening with a Health Professional," is an evening of interaction with different health professionals, affording participants the opportunity to gain an in-depth understanding of a specific area of clinical activities, teaching or research.
The second session, on April 11, will focus on "The Heart: Health and Repair." This discussion will feature diseases of the heart and innovative treatment approaches coming into use. Presenters will include noted pediatric heart surgeon Dr. John Calhoon.
The third session, on April 18, describes "The Brain: A User's Guide." The discussion will concentrate on diseases of the brain and innovative treatment approaches, with presenters including a cell biologist, neurologist and neurosurgeon.
The final session, on April 25, is called "Living with Illness." Patients with heart and brain disease will share their stories about how they have learned to live with their illness. Health professionals who work with chronically ill or terminally ill patients will contribute their perspectives.
The Mini-Medical School is supported in part by an educational
grant from Pfizer.
International Alliance to host food tasting
The Health Science Center's International Alliance is hosting an international food tasting at 7 p.m. Friday, March 24, in the Dental School cafeteria. Light refreshments will be provided by the alliance, and participants are asked to bring a plate of food to share that is representative of their home country.
A program on South Korea will follow the event. For more information, contact Jennifer Orr at 344-5547.
Outstanding teacher nominees sought
Nominations are being taken for the Health Science Center's 2000 Presidential Awards for Teaching Excellence. Each year the institution honors up to six faculty members who have demonstrated outstanding accomplishments in teaching. To be eligible, a nominee must be a full-time faculty member and have taught for a minimum of three consecutive years (as of Sept. 1, 1999). Nominees cannot have received the award within the past eight years.
Faculty members may be nominated by three students or house officers, two faculty members or a department chairperson. Nomination forms may be obtained from department chairs or the president's office. Completed forms must be turned in to Dr. Deborah Greene, vice president for institutional effectiveness and planning, by Friday, March 31.
Miles for Smiles run scheduled for March 25
The Health Science Center Dental School Miles for Smiles 5K run, 2K walk, kids run and health fair will be held Saturday, March 25, at the university pavilion near the track. Registration begins at 7 a.m. and the 5K run starts at 8 a.m. The 2K walk will follow at 8:15 a.m. and the Kids Run will start at 9:15 a.m. A health fair and awards ceremony will be held after the races.
The event is designed to help educate and promote good oral health. The money raised will be returned to the community through dental programs, which include the school-based fluoride rinse program, preventive sealant program and dental care services for underserved areas of San Antonio.
Registration is $15 for adults on race day and $8 for children 12 and under. Each person who registers will receive an official Miles for Smiles commemorative T-shirt and is eligible to win various door prizes.
Cash prizes of up to $75 will be awarded for overall winners, and awards will be presented for the top three finishers in several age groups. For more information, call ext. 7-3752.
Equipment auction set for April
A public auction of surplus/obsolete property is scheduled for 9 a.m. Saturday, April 8, in the Health Science Center General Services warehouse. Items for auction include medical equipment, shelving, desks, typewriters and calculators. Refreshments will be sold during the event.
A viewing of the items is set for 8 a.m. to 5 p.m. Friday, April 7, and from 8 a.m. to 9 a.m. the day of the auction. Items placed in the auction will be available for transfer at no charge to any Health Science Center department through Friday, March 31. For more information, call ext. 7-6021.
Ultimate frisbee offered
Ultimate frisbee is available to interested individuals at the Health Science Center. The game is played on a field with dimensions similar to football and includes elements of various sports.
For more information or to register, contact Dr. Sergio Rivas at ext. 7-7810 or by e-mail at firstname.lastname@example.org.
Mark your calendar for a host of fun and educational events involving the Health Science Center this spring:
Monday, March 20
7:00 a.m. Orthopaedic Teaching Conf. "Common Causes of Low Back Pain in Children" (MED: 309L)
8:00 a.m. Rehab Medicine Lecture Series "Geriatric Rehabilitation Exercise Programs: A Review of the Literature," Drs. David LeMay & Mark Fredrickson (UH: Reeves Rehab Center 3rd-floor classroom)
8:00 a.m. Medical Housestaff Specialty Conf. "Residents & Interns: M&M" (MED: 409L)
Tuesday, March 21
6:30 a.m. Podiatry Grand Rounds "Midfoot/Rearfoot Trauma," Dr. Suhad Hadi (MED: 209L)
8:00 a.m. Rehab Medicine Lecture Series "Knee: Major Clinical Syndromes," Drs. James Williams & Mark Fredrickson (UH: Reeves Rehab Center 3rd-floor classroom)
8:00 a.m. Medical Housestaff Specialty Conf. "Fungal Infections," Dr. Patterson (MED: 309L)
9:00 a.m. Training Office "Library Pathways," Cathy Rhodes (Briscoe Library room 2A) (call ext. 7-2320 for information or to register)
Noon. TNT "Hematology: Hematologic Disorders in HIV Patients: Clinical Update," Dr. Carmen Julius, Butler Memorial Hospital, Butler, Pa. (call ext. 7-2700 for information)
Noon. Medicine Research Conf. "Salt & Blood Pressure: New Insights from Human Genetic Studies," Dr. Richard Lifton, Yale University School of Medicine (MED: 209L)
1:15 p.m. Psychiatry Grand Rounds "Turmoil & Opportunity in ECT: A Millennial Update," Dr. Max Fink, Albert Einstein College of Medicine (MED: 409L)
1:30 p.m. TNT "Infectious Diseases: Emerging Nosocomial Fungal Pathogens," Dr. Elias Anaissie, University of Arkansas Medical School (call ext. 7-2700 for information)
4:00 p.m. Molecular Medicine Seminar "Chromatin Remodeling Machines: Control of Gene Expression in Mitosis," Dr. Craig Peterson, University of Massachusetts Medical School (IBT: 3.002)
4:00 p.m. Interdisciplinary Cardiovascular Research Conf. "Three Isoforms of Nitric Oxide Synthase & How They Work," Dr. Bettie Sue Masters (MED: 409L)
Tuesday, March 22
6:30 a.m. Podiatry Case Conf. (MED: 309L)
7:00 a.m. Vascular Surgery Grand Rounds, Dr. Mellick Sykes (MED: 209L)
8:00 a.m. Medical Grand Rounds "The Role of Inflammation & Infection in Acute & Chronic Coronary Syndromes," Dr. Marschall Runge, U. T. Medical Branch (MED: 409L)
9:00 a.m. Surgery Trauma M&M Conf., Dr. Ronald Stewart (MED: 309L)
10:30 a.m. TNT "Women's Health Issues & Trends: Breast Cancer: An Update on Evaluation & Therapy," Dr. Robert Goulet, Indiana University Breast Cancer & Research Center (call ext. 7-2700 for information)
Noon. Pharmacology Seminar Series "The Effects of Fluvoxamine on the Behavioral Actions of Ethanol," Dr. Richard Lamb (MED: 444B)
1:00 p.m. Training Office "Reading Ledger Sheets," Donna Henckel (call ext. 7-2320 for information or to register)
Thursday, March 23
7:30 a.m. Thoracic Surgery Resident Teaching Conf. (VA: 4th-floor CT Library A404)
8:00 a.m. Neurology Grand Rounds "New Directions in the Management of Multiple Sclerosis," Dr. Barry Arnason, University of Chicago (MED: 444B)
8:00 a.m. Medical Housestaff Specialty Conf. "Glomerulonephritis," Dr. Balakuntalam Kasinath (MED: 409L)
Noon. Pulmonary, Thoracic & Oncology Conf. (MED: 309L)
12:30 p.m. TNT "Pain Management: Interdisciplinary Conference: Cancer Pain Case Review," Alison Beck & Drs. Hasi Venkatachalam, Mary Heye and Clayton Gable (call ext. 7-2700 for information)
3:00 p.m. Surgery Tumor Conference, Dr. Anatolio Cruz (MED: 209L)
4:30 p.m. Citywide Thoracic Grand Rounds "Quality Surgery," Dr. Philip Lisagor, Brooke Army Medical Center (MED: 309L)
5:00 p.m. Plastic & Reconstructive Surgery Grand Rounds "Eyelid Reconstruction," Dr. Robert Kessler (MED: 409L)
Friday, March 24
7:30 a.m. Pediatric Grand Rounds "Is It Milk Allergy or Lactose Intolerance?" Dr. Sami Bahna, University of South Florida (MED: 409L)
8:00 a.m. Medical Housestaff Specialty Conf. "Plasma Cell Dyscrasias Monoclonal Gammopathies," Dr. Alsina (LEC: 2.030)
8:00 a.m. Rehab Medicine Lecture Series "Resolution of RSD After Subarachnoid Space Reconstruction: A Review of Research," Drs. Erik Kussro & Douglas Barber (UH: Reeves Rehab Center 3rd-floor classroom)
8:30 a.m. Cardiovascular Research Conf., Lee Ann Bennett (LEC: 3.078V)
Saturday, March 25
7:15 a.m. Surgical Physiology Conf., Dr. Kenneth Sirinek (MED: 209L)
9:00 a.m. General Surgery Grand Rounds, Dr. Wayne Schwesinger (MED: 209L)