Academic Program Coordinator
c/o Department of Pharmacology, UTHSCSA
7703 Floyd Curl Dr.
Mail Code: 7764
San Antonio, TX. 78229-3900
Texas State University, San Marcos, Texas
David Morilak, Ph.D.
Photography, Gardening/Landscaping and Hitting up the gym
Julianne is investigating the mechanisms by which chronic stress can lead to deficits in cognitive flexibility related to dysfunction of the medial prefrontal cortex. She utilizes behavioral pharmacological techniques, in situ hybridization, microdialysis, neuroanatomical measures, and sophisticated behavioral assays of cognitive function to address the interactions of noradrenergic modulatory function with glutamate signaling that underly stress-induced pathology and its treatment.
Translational Science Training Award - Institute for Integration of Science and Medicine (IIMS) - 2012/2013
Neural mechanisms of chronic stress-induced cognitive deficits in the rat prefrontal cortex: implications for novel therapies in the treatment of depression
2011 - Present - International Behavioral Neuroscience Society
2008 - Present - Society for Neuroscience (SfN)
2007 - Present - American Society for Pharmacology and Experimental Therapeutics (ASPET)
Doyen, J. and Morialk, DA. Too Much of a Good Thing: Blocking Noradrenergic Facilitation in Medial Prefrontal Cortex Prevents the Detrimental Effects of Chronic Stress on Cognition. Neuropsychopharmacology, doi: 10.1038/npp.2012.216. [Epub ahead of print] (2012) PMID:23132268.
Bondi, CO., Jett, JD. and Morilak, DA. Beneficial effects of desipramine on cognitive function of chronically stressed rats are mediated by α1-adrenergic receptors in medial prefrontal cortex. Prog Neuropsychopharmacol Biol Psychiatry, 34, 913-923 (2010) PIMD: 20417676.
Lapiz-Bluhm, MDS., Bondi, CO., Doyen, J., Rodriguez, G., Bedard-Arana, T. and Morialk, DA. Behavioral assays to measure congnative and affective dimensions of depression and anxiety in rats. J Neuroendocrinol, 20, 1115-1137 (2008) PIMD: 18673411.
Society for Neuroscience Annual Conference - Washington, D.C. - Fall 2011
Jett, JD. and Morilak, DA. Changes in prefrontal cortical response to thalamic afferent activation: a potential mechanism for stress-induced cognitive deficits in rats. (Poster)
Society for Neuroscience Chapter Symposium - San Antonio, TX. - 2010
Jett, JD. and Morilak, DA. Assessing prefrontal cortical network activity: An indicator of stress-induced cognitive deficits in rats. (Poster)
Society for Neuroscience Annual Conference - Washington, D.C. - Fall 2008
Jett, JD., Bedard, T., Rodriguez, G. and Morilak, DA. Blockade of adrenergic receptors during chronic unpredictable stress prevents the detrimental effects on cognitive flexibility in rats. (Poster)
Bondi, CO.,Jett, JD. and Morilak, DA. Effects of acute atipamezole treatment on performance in an attentional set-shifting test after chronic unpredictable stress. (Poster)
Lapiz, M.,Jett, JD., Rodriguez, G. and Morilak, DA. Temporal characterization of the cognitive deficit induced by chronic intermittent cold stress on an attentional set-shifting test in rats. (Poster)
Baganz, NL., Carneiro, AMD., Horton, RE., Alvarado, SR.,Jett, JD., Owens, WA., Blakely, RD. and Daws, LC. Reduced serotonin clearance in hippocampus after forced swim: is a “stressed-out” serotonin transporter to blame? (Poster)
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