Microbiology, Immunology & Molecular Genetics| Faculty
Highslide JS Ricardo C.T. Aguiar,
M.D., Ph.D.

Professor
Department of Medicine/ Hematology & Medical Oncology,
Microbiology, Immunology & Molecular Genetics
(Biochemistry)

aguiarr@uthscsa.edu
(210) 567-4869

Dr. Aguiar's lab focuses on clinical training in Hematology/Oncology. Dr. Aguiar has a PhD in the field of leukamia and lymphoma biology, normal/malignant B cell biology and molecular/cellular pathogenesis of B cell lymphoma.

Highslide JS Sunil K. Ahuja, M.D.  
Professor
Department of Medicine/ Infectious Disease
Microbiology, Immunology & Molecular Genetics

ahujas@uthscsa.edu   
(210) 567-6511

Dr. Ahuja's lab focuses on CCR5 gene regulation, host genetic determinants of HIV-AIS susceptibility, influence of treatment timing and host immune-genetic determinants on response to anti-HIV therapy and vaccines, and allergen challenge chamber studies.

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Bernard P. Arulanandam, Ph.D.
Adjunct Professor
UTSA
Biological Sciences
(UTHSCSA SoM, Microbiology, Immunology & Molecular Genetics)

barulanandam@utsa.edu  
(210) 458-5492

Dr. Arulanandam's research involves elucidating host-microbial interactions and induction of immune responses against infectious diseases. His current project include studies involving pathogenesis of Chlamydia trachomatis and Acinetobacter baumannii.

Joel B. Baseman, Ph.D.
Professor
Microbiology, Immunology & Molecular Genetics
Surgery
Medicine

baseman@uthscsa.edu   
(210) 562-4190

Dr. Baseman's lab examines virulance determinants of human mycoplasmas and host responses to infection, with special interest in the ADP-ribosylating and vacuolating CARDS toxin of M. pneumoniae and invasive properties of M. genitalium.

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Michael T. Berton, Ph.D.
Associate Professor
Microbiology, Immunology & Molecular Genetics

berton@uthscsa.edu   
(210) 567-3931
Dr. Berton's lab is interested in the host cell signaling pathways, particularly Toll-like receptor signaling pathways, that regulate immune responses. His lab also studies the mechanisms that pathogens use to manipulate and evade host immunity.

Edward G. Brooks, M.D.
Professor
Pediatrics/Immunology and Infectious Diseases,
Microbiology, Immunology & Molecular Genetics

brookse@uthscsa.edu  
(210) 567-5250

Dr. Brook's lab focuses on clinical research experience in immunology with broad experience in human immuna and allergic disorders and has performed investigations of animal and human lymphocyte phenotypic studies and biomarker analysis.
Highslide JS Renee M. Brown, Ph.D.
Director of Curriculum

brownr5@uthscsa.edu   
(210) 567-6069
Director of Curriculum with oversight of all four years of the Undergraduate Medical Education program for the School of Medicine.

Evelien M. Bunnik, Ph.D.
Assistant Professor
Microbiology, Immunology & Molecular Genetics

bunnik@uthscsa.edu
(210) 450-8146

Dr. Bunnik's overall goal of her research is to understand protective immunity in malaria-exposed individuals and to use this knowledge for the design of a novel, effective malaria vaccine. She proposed to screen and clone antibodies from protected individuals living in malaria-endemic regions to enable further characterization of antibodies reactive against the malaria parasite.
Highslide JS Astrid E. Cardona, Ph.D.
Adjunct Associate Professor
Biological Sciences
UTSA
(UTHSCSA SoM, Microbiology, Immunology & Molecular Genetics)

astrid.cardona@utsa.edu  
(210) 458-5071

Dr. Cardona's lab focuses on understanding the role of fractalkine and its receptor CX3CR1 in the regulation of CNS pathology during chronic inflammation using experimental models of Multiple Sclerosis and continues to provide evidence for modulators of microglial activation.

Highslide JS Paolo Casali, M.D.
Professor & Chairman
Microbiology, Immunology & Molecular Genetics
(Medicine)

pcasali@uthscsa.edu
(210) 567-3950
Dr. Casali's research focuses on mechanisms of immunoglobulin locus activation and targeting, as well as regulation of genome-wide and specific gene expression by epigenetic marks and gut microbiota, in antibody/autoantibody responses and immune memory.
Yidong Chen, Ph.D.
Professor
Department of Epidemiology & Biostatistics
Microbiology, Immunology & Molecular Genetics
University of Texas Health Science Center San Antonio

cheny8@uthscsa.edu
(210) 562-3961

Dr. Chen's research focuses on bioinformatics, computational modeling, and biostatistics for the application of gene expression, miRNA, DNA copy number, SNP and other genome-wide profiling for cancer research, especially for pediatric cancer studies.
Robert A. Clark, M.D., MACP
Professor
Office of the VP for Research
Medicine
Microbiology, Immunology & Molecular Genetics
(Physiology) (South Texas Veterans Health Care System)

clarkra@uthscsa.edu
(210) 567-0866

Dr. Clark's research emphasizes both basic & translational research approaches to issues relevant to human diseases, with a major focus on mechanisms of inflammatory response and oxidative stress, as well as the cell biology and biochemistry of human phagocytic cells.

Tyler J. Curiel, M.D., M.P.H.
Professor
Medicine/Hematology and Medical Oncology
Microbiology, Immunology & Molecular Genetics

curielt@uthscsa.edu
(210) 450-5882

Dr. Curiel's lab focuses on expertise in tumor immunology and immunotherapy and human immunology with an emphasis on understanding the immunopathologic basis of human diseases including cancer, infections and autoimmunity.

Highslide JS Benjamin J. Daniel, Ph.D.
Associate Professor/Research
Microbiology, Immunology & Molecular Genetics
Director, Flow Cytometry Core Facility

danielb@uthscsa.edu   
(210) 567-3911

Dr. Daniel is the director of the Flow Cytometry Facility and is involved in instrumentation, experimental design and data interpretation technology. His lab studies dysfunction of aged immune systems in response to cancer and modulation of T cell exhaustion.

Highslide JS Robert A. Davey, Ph.D.
Adjunct Professor
Southwest National Primate Center
(UTHSCSA SoM, Microbiology, Immunology & Molecular Genetics)

rdavey@txbiomed.org  
(210) 258-9826

Dr. Davey's lab focuses on high throughput screens of siRNA, small molecules, and microscopy performed at BSL4 that are combined to identify host proteins used by Ebolavirus to understand infection mechanism and find drugs that can be used as treatments.
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Peter H. Dube, Ph.D.
Associate Professor
Microbiology, Immunology & Molecular Genetics

dube@uthscsa.edu
(210) 562-4181

Dr. Dube's lab focuses on the immuno-biology of infectious disease. The lab investigates the role of bacterial virulance factors in the modulation of inflammatory responses at mucosal surfaces and the role of these processes in human disease.

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Thomas G. Forsthuber,
M.D., Ph.D.
Adjunct Professor
Biological Sciences
UTSA
(UTHSCSA SoM, Microbiology, Immunology & Molecular Genetics)

thomas.forsthuber@utsa.edu   
(210) 458-5760

Dr. Forsthuber's lab focuses on better understanding the mechanisms of T cell-mediated immunopathology in experimental models of human autoimmune diseases (EAE, EAM), development of new treatments, and identifying better disease biomarkers.

Highslide JS Marie-Claire E. Gauduin, Ph.D.
Adjunct Associate Scientist
Virology & Immunology
TBRI
(UTHSCSA SoM, Microbiology, Immunology & Molecular Genetics)

mcgauduin@txbiomed.org   
(210) 258-9844

Dr. Gauduin's research includes investigation of host immune responses to infectious diseases using macaques focusing on mechanisms of transmission, early immune responses, development of therapeutic and vaccine strategies and development of a neonatal TB/macaque model to study TB/SIV co-infection in pediatric AIDS.
Highslide JS Luis D. Giavedoni, Ph.D.
Adjunct Professor
Scientist and Vice Chair
Virology & Immunology, Southwest National Primate Research Center
(UTHSCSA SoM, Microbiology, Immunology & Molecular Genetics)

lgiavedo@txbiomed.org   
(210) 258-9603

Dr. Giavedoni's lab focuses on the role and function of cytokines, molecules that mediate communication between the immune system and the whole organism. His research group has been developing technology for the identification of cytokines in nonhuman primates and also studying the potential use of these molecules to modify the outcome of immune responses.
Highslide JS Francisco González-Scarano, M.D.
Professor
Department of Neurology
Dean – School of Medicine

scarano@uthscsa.edu   
(210) 567-4663
Dr. Gonzalez is a national recognized leader in neurology. He also has significant experience in improving delivery of care in a large health care system, as well as experience in strategic and financial planning. He possesses a balanced enthusiasm for the scientific, clinical and educational missions of an academic enterprise.
Ann V Griffith Ann V. Griffith, Ph.D.
Assistant Professor
Microbiology, Immunology & Molecular Genetics

griffithA3@uthscsa.edu   
(210) 567-3978

Dr. Griffith's research interests lie in the identification of lymphopoietic signals provided by the stromal micro environment in the thymus, the biology of thymic stromal cells, and the mechanisms and consequences of age-induced thymic atrophy.
Highslide JS Anthony Griffiths, Ph.D.
Adjunct Assistant Professor
Virology & Immunology
TBRI
(UTHSCSA SoM, Microbiology, Immunology & Molecular Genetics)

agriffiths@txbiomed.org   
(210) 258-9557

Dr. Griffiths' studies highly pathogenic viruses with a focus on filoviruses. This work includes animal model development, determination viral growth requirements, virus particle characterization, translational control, and genomics.
Highslide JS M. Neal Guentzel, Ph.D.
Adjunct Professor
Biological Sciences
UTSA
(UTHSCSA SoM, Microbiology, Immunology & Molecular Genetics)

Neal.Guentzel@utsa.edu   
(210) 458-4473


Dr. Guentzel's lab focuses on pathogenesis, host responses (both innate and adaptive immunity) and vaccine development for the important human pathogens Francisella tularensis, a select agent and the cause of tularemia in humans, and Chlamydia trachomatis, the major bacterial sexually transmitted pathogen
P. John Hart, Ph.D.
Professor
Biochemistry
Microbiology, Immunology & Molecular Genetics
Director, X-ray Crystallography Core Laboratory

pjh@biochem.uthscsa.edu  
(210) 567-0751

Dr. Hart is a trained biochemist and macromolecular crystallographer and studies the use of biochemical and biophysical methods to understand the structure of proteins relevant to human health, with emphasis on proteins involved in neurodegeneration, and bacterial and parasite pathogenesis.
Andrew Hayhurst, Ph.D.
Adjunct Professor
Virology & Immunology
TBRI
(UTHSCSA SoM, Microbiology, Immunology & Molecular Genetics)

ahayhurst@txbiomed.org   
(210) 258-9530

Dr. Hayhurst has a variety of translational interests including antibody engineering, emerging pathogen countermeasures, tumor targeting and nanotechnology and we also pursue mechanisms of antibody binding and structure guided design.

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Dmitri N. Ivanov, Ph.D.
Associate Professor
Biochemistry
Microbiology, Immunology & Molecular Genetics

ivanov@uthscsa.edu   
(210) 567-8781
Dr. Ivanov's research is focused on elucidating molecular mechanisms involved in HIV pathogenesis and DNA repair using methods of structural biology and biochemistry.
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Victor X. Jin, Ph.D.  
Associate Professor
Molecular Medicine
Epidemiology & Biostatistics
Microbiology, Immunology & Molecular Genetics

jinv@uthscsa.edu 
(210) 562-9209
Dr. Jin's lab focuses on developing computational approaches for the identification and characterization of genomic regulatory elements and networks fromt he cancer epi-genomic and genomic regulatory data generated from next generation sequencing (NGS) technologies. His lab also focuses on functionally validating the computational predictions and providing meaningful biological interpretations using novel techniques.
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David Kadosh, Ph.D.  
Associate Professor
Microbiology, Immunology & Molecular Genetics

kadosh@uthscsa.edu   
(210) 567-3976
Dr. Kadosh's lab focuses on molecular mechanisms that control morphology, virulence and biofilm formation in pathogenic Candida species. We use a wide variety of approaches, including molecular biology, genetics, biochemistry and genomics.
William J. Kaiser, Ph.D.
Associate Professor
Microbiology, Immunology & Molecular Genetics

kaiserw@uthscsa.edu
(210) 567-0706
Dr. Kaiser's lab focuses on defining the molecular basis of programmed necrosis through dissecting innate immune signal transduction pathways upstream and downstream of caspase 8/RIP1/RIP3, identifying new cellular programmed necrosis signaling components and viral modulators, and developing strategies for therapeutic intervention.
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T. R. Kannan, Ph.D.
Associate Professor/Research
Microbiology, Immunology & Molecular Genetics

kannan@uthscsa.edu   
(210) 562-4182
Dr. Kannan's laboratory studies the pathogenesis of two small bacterial pathogens, Mycoplasma pneumoniae through CARDS toxin and the mechanisms by which Mycoplasma genitalium adheres, internalizes and survives within host cells.
Su Yu Tsai

Marsha Kinney, M.D.
Professor & Chairman
Pathology
Microbiology, Immunology & Molecular Genetics

kinneym@uthscsa.edu   
(210) 567-4098

The laboratory of Dr. Kinney studies subjects in hematopathology. She specifically specializes in anaplastic large cell lymphoma, cutaneous hematopoietic and lymphoid neoplasms, extranodal T- and NK-cell lymphoma, and hematopathology.
Su Yu Tsai
Karl E. Klose, Ph.D.
Adjunct Professor
Biological Sciences
UTSA
(UTHSCSA SoM, Microbiology, Immunology & Molecular Genetics)

karl.klose@utsa.edu   
(210) 458-6140

Dr. Klose's lab is interested in bacterial pathogenesis, how bacteria cause disease. Dr. Klose has worked most extensively with Vibrio cholerae, the bacterium that causes cholera, and has also researched Francisella tularensis, the bacterium that causes tularemia, or rabbit fever.
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David J. Kolodrubetz, Ph.D.
Professor
Microbiology, Immunology & Molecular Genetics

kolodrubetz@uthscsa.edu   
(210) 567-3967
Dr. Kolodrubetz' underlying theme of his lab's research efforts have been to develop and use molecular, genetic, genomic and biochemical approaches to elucidate the functions and regulation of virulence factors in periodontal pathogens.
Highslide JS Ellen B. Kraig, Ph.D.
Professor
Cellular & Structural Biology
Microbiology, Immunology & Molecular Genetics

kraig@uthscsa.edu   
(210) 567-3818

Dr. Kraig studies the effects of aging on immunity and autoimmunity with the goal of improving vaccine efficiency in the elderly. She also investigates the role of the microbiome in development of immune competence both in young and old.

Keith A. Krolick, Ph.D.
Professor
Distinguished Teaching Professor
Microbiology, Immunology & Molecular Genetics

krolick@uthscsa.edu   
(210) 567-3968
Dr. Krolick shifted his emphasis from laboratory research to the educational and administrative missions of the department. He teaches in all five schools of the Health Science Center, in both basic science and pre-clinical science courses for PhD and MS students, and for medical, dental, and nursing students.

Robert E. Lanford, Ph.D.
Director of Southwest National Primate Research Center and Scientist
Virology & Immunology
TBRI
(UTHSCSA SoM, Microbiology, Immunology & Molecular Genetics)

rlanford@txbiomed.org   
(210) 258-9445

Dr. Lanford's laboratory's primary focus is to better understand the interactions of the hepatitis B virus (HBV), hepatitis C virus (HCV) and GBV-B, a surrogate model for HCV respectfully with the host, and how it influences either viral clearance or persistence and disease progression.
Zhao Lai, Ph.D.
Director
Genome Sequencing Facility
Faculty Associate
Microbiology, Immunology & Molecular Genetics

laiz@uthscsa.edu   
(210) 562-9246

Dr. Lai manages internal/external collaborations in strategic planning and execution of sequencing projects and performed high-throughput sample preparation and large-scale sequencing (genome, transcription, exome, methylome, ChIP, small RNA).

Elizabeth A. Leadbetter, Ph.D.
Associate Professor
Microbiology, Immunology & Molecular Genetics

Leadbetter@uthscsa.edu   
(210) 567-3923

Dr. Leadbetter studies invariant NKT and B cell cooperation. The lab strives to understand the mechanism and outcome of the cellular interplay and to harness this cooperation for the development of a universal lipid-based vaccine.

Xiao-Dong Li, M.D., Ph.D.
Assistant Professor
Microbiology, Immunology & Molecular Genetics

LiX8@uthscsa.edu   
(210) 567-3986
Dr. Li's lab is focused on studying the role of innate immune sensing of nucleic acids DNA/RNA in host defense and inflammation. Ongoing work addresses the in vivo functions of innate immune sensing of RNA/DNA in either physiological or pathological contexts.
Jose L. Lopez-Ribot, Ph.D.
Adjunct Professor
Biological Sciences
UTSA
(UTHSCSA SoM, Microbiology, Immunology & Molecular Genetics)

jose.lopezribot@utsa.edu   
(210) 458-7022


Dr. Lopez-Ribot studies the immunopathogenesis of fungal infections with an emphasis on the opportunistic pathogenic fungus Candida albicans, fungal biofilms, and antifungal drug development.

Phillip T. LoVerde, Ph.D.
Professor
Biochemistry
Pathology
Microbiology, Immunology & Molecular Genetics
(Southwest National Primate Research Center)

loverde@uthscsa.edu   
(210) 567-3737
Dr. LoVerde's research involves studies of host parasite interactions of schistosomes with strengths in molecular parasitology, immunoparasitology and genetics. Recent study-identification of the gene responsible for oxamniquine drug resistance.
Stanton F. McHardy, Ph.D.
Director
Center for Innovative Drug Discovery
Department of Chemistry,
University of Texas San Antonio

stanton.mchardy@utsa.edu   
(210) 567-0349
Dr. McHardy’s lab and the CIDD are focused on medicinal chemistry research in the design, synthesis and development of small molecule compounds across multiple therapeutic disease areas.
Xiangzhi Meng, Ph.D.
Assistant Professor/Research
Microbiology, Immunology & Molecular Genetics

meng@uthscsa.edu   
(210) 567-0349
Dr. Meng's lab focuses primarily on vaccinia virus. Vaccinia virus is the protypical poxvirus and serves as the vaccine for smallpox. Poxviruses included some dangerous emerging or re-emerging pathogens as well as some promising vaccine vectors for infectious diseases and cancers.
Jean L. Patterson, Ph.D.
Adjunct Professor
Virology & Immunology
TBRI
(UTHSCSA SoM, Microbiology, Immunology & Molecular Genetics)

jpatters@txbiomed.org
  
(210) 258-9431

Dr. Patterson's lab develops vaccines & therapeutics against highly lethal viral pathogens and determines how they replicate and spread through basic applied research. She is also researching Filovirus vaccine development and filovirus host-pathogen defense.

Luiz O. Penalva
Associate Professor
Cellular & Structural Biology
Microbiology, Immunology & Molecular Genetics

penalva@uthscsa.edu
(210) 562-9049
Dr. Penalva's lab has been working on NIH funded projects to characterize RBP target genes and pertinent regulatory sequences genome-wide in human cells. Projects rely on biochemical methods that consist in isolating RNA-protein complexes of interest followed by characterization of the RNA component by CLIP (Cross-Linking and Immuno-Precipitation) or RIP (Ribonucleoprotein Immuno-Precipitation) sequencing.

Sophia Pina, Ph.D.
Assoc. Dean for Student Affairs
School of Osteopathic Medicine
University of the Incarnate Word

sepina@uiwtx.edu
(210) 283-6388

Dr. Pina is an alumni of the Department of Microbiology, Immunology & Molecular Genetics. She has taught extensively in the School of Medicine and Dental School proceeding medical and clinical microbiology lectures and laboratories. She also played a role in recruitment, admissions, implementation, coordination, mentoring and graduation of students in the program.
Highslide JS Blanca I. Restrepo, Ph.D.
Adjunct Associate Professor

Blanca.i.restrepo@uth.tmc.edu
(956) 279-3841
Dr. Restrepo's laboratory is in South Texas, adjacent to the Mexican border. The lab is currently focusing on evaluating the impact of diabetes on TB control by conducting epidemiological and basic science studies. The long-term goal is to identify strategies for prevention of TB among diabetic patients.
Highslide JS Ruth M. Ruprecht, M.D., Ph.D.
Scientist and Professor
Virology & Immunology
TBRI
(UTHSCSA SoM, Microbiology, Immunology & Molecular Genetics)

Rruprecht@txbiomed.org   
(210) 258-9568
Dr. Ruprecht's lab studies lentiviral pathogenesis, the prevention of mother-to-child transmission of HIV-1, and AIDS vaccine development, especially against HIV clade C (HIV-C) primate models play an essential role in this work.

Paula K. Shireman, M.D.
Professor
Vice Dean for Research
Surgery
Microbiology, Immunology & Molecular Genetics

shireman@uthscsa.edu
(210) 567-5715

Dr. Shireman's lab studies epigenetic regulation of macrophages polarization and stem cell function via microRNAs. Her long term goal is to develop macrophage-mediated therapies to enhance muscle regeneration and angiogenesis, thereby reducing limb amputations.

Alexei V. Tumanov, M.D., Ph.D. 
Associate Professor
Microbiology, Immunology & Molecular Genetics

tumanov@uthscsa.edu
(210) 450-8157

Dr. Tumanov's research focuses on the regulation of mucosal immunity and homeostasis of lymphoid organs in the host response to pathogens.
Brian L. Wickes, Ph.D.
Professor
Microbiology, Immunology & Molecular Genetics

wickes@uthscsa.edu   
(210) 567-3938

Dr. Wickes' lab focuses on morphology and differentiation in Cryptococcus neoformans, and how this process affects virulence. We use genetics, molecular biology, microscopy and next generation sequencing to understand these processes.

Nathan Wiederhold, Pharm.D.
Director, Fungus Testing Laboratory
Associate Professor
College of Pharmacy, UT Austin
(UTHSCSA SoM, Microbiology, Immunology & Molecular Genetics)

wiederholdn@uthscsa.edu   
(210) 567-4086
Dr. Wiederhold's research is focused on trends in antifungal resistant, new mechanisms of drug resistance in fungi, and in the evaluation of novel agents under development for the treatment of invasive fungal infections.
Yan Xiang, Ph.D.
Associate Professor
Microbiology, Immunology & Molecular Genetics

xiangy@uthscsa.edu   
(210) 567-0884

Dr. Xiang's lab focuses on immune evasion mechanisms of poxviruses and discoveries of poxvirus interleukin-18 binding protein.

Zhenming Xu, Ph.D.
Assistant Professor
Microbiology, Immunology & Molecular Genetics

xuz3@uthscsa.edu   
(210) 567-3964
Dr. Xu's lab investigates the role of intercellular membranes and associated proteins in B cell differentiation and antibody responses to pathogens and vaccines as well as show dysregulation of these elements leads to autoimmunity and lymphomagenesis.
Hong Zan, Ph.D.
Associate Professor/Research
Microbiology, Immunology & Molecular Genetics

zan@uthscsa.edu   
(210) 567-3971
Dr. Zan's current research is focused on the roles of the epigenetic marks (including DNA modifications), histone acetylation and microRNA, transcription factors and DNA repair proteins in these B cell specific processes, and the regulation of these elements by genetic, hormonal and environmental factors.
Nu Zhang, Ph.D.
Assistant Professor
Microbiology, Immunology & Molecular Genetics

zhangN3@uthscsa.edu   
(210) 567-3971
Dr. Zhang's lab focuses on the biology and function of tissue-resident memory T cells and tumor infiltrating T cells in health and disease, and the role of TGF-b signaling in their differentiation, homeostasis and metabolic regulations.
Guangming Zhong, M.D., Ph.D.
Professor
Microbiology, Immunology & Molecular Genetics

zhongg@uthscsa.edu   
(210) 567-1169
Dr. Zhong's lab has been using chlamydial infection in the female genital tract as a model to investigate the mechanisms of inflammatory pathology and pathogenic fibrosis so that reagents/strategies can be developed to improve diagnosis, intervention and prevention of these pathologies.

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Updated 09.14.2016