Microbiology, Immunology & Molecular Genetics Faculty
Ben Daniel, Ph.D.
5.044V - MED
Ph.D., Biomedical Studies (Immunology Track) at Baylor University
Keywords: Flow Cytomerty
Dr. Benjamin J. Daniel is the Director of the Institutional Flow Cytometry Facility and a Research Assistant Professor in the department of Molecular Medicine at the University of Texas Health Sciences Center at San Antonio (UTHSCSA). He has more than 16 years of experience in flow cytometry and immunological research in the context of host/pathogen immune responses. More recently, his research entailed studying the dysfunction of the aged immune system in response to cancer. His current research includes modulation of T cell exhaustion to improve anti-cancer therapies in aging. His previous research included the study of tumor immune dysfunction, or how the tumor subverts one’s normal immunity into benefiting that of the tumor. He currently serves on the Flow Cytometry Core Managers Task force for the International Society for Analytical Cytometry (ISAC). He is also on the organizational committee for FlowTex; a Texas-based annual flow cytometry conference.
Awards and Accomplishments
Tulane Cancer Center Matching funds Awards, Tulane Cancer Center provided matching salary support
|2005||17th Annual Tulane University HSC Award for Research in Infectious Diseases|
- Member of the International Society for the Advancement of Cytometry (ISAC)
- Member, The American Association of Immunologist (AAI)
- Brumlik, M. J., S. Pandeswara, S. M. Ludwig, D. P. Jeansonne, M. R. Lacey, K. Murthy, B. J. Daniel, R.-F. Wang, S. R. Thibodeaux, K. M. Church, V. Hurez, M. J. Kious, B. Zhang, A. Alagbala, X. Xia, and T. J. Curiel. 2013. TgMAPK1 is a Toxoplasma gondii MAP kinase that hijacks host MKK3 signals to regulate virulence and interferon-γ-mediated nitric oxide production. Exp. Parasitol. 134: 389–399.
- De Angulo, A., Faris, R., Cavazos, D., Jolly, C., Daniel, B., & DeGraffenried, L. (2013). Age-related alterations in T-lymphocytes modulate key pathways in prostate tumorigenesis. Prostate, 73(8), 855–864. doi:10.1002/pros.22631s
- Daniel, B. J., Hurez, V., Sun, L., Liu, A.J., Ludwig, S.M., Kious, M.J., Thibodeaux, S.R., Pandeswara, S., Murthy, K., Livi, C.B., Wall, S., Brumlik, M.J., Shin, T., Zhang, B., Curiel, T.J., 2012. Mitigating age-related immune dysfunction heightens the efficacy of tumor immunotherapy in aged mice. Cancer research 72:2089-2099.
- Daniel, B. J., Pandeswara, S., Brumlik, M. J., Liu, A., Thibodeaux, S. R., Ludwig, S. M., Sun, X., Curiel, T. J. 2010 “A simple method to detect Toxoplasmagondii-specific cytotoxic T cells in vivo”, J Immunol Methods, 355:86-90.
- Jin, D., Fan, J., Wang,L., Thompson, L. F., Liu,A., Daniel,B. J., Shin, T., Curiel,T. J., and Zhang, B., 2010 “CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression”,Cancer Res, 70:2245-2255.
- Rüter, J., Barnett, B.G., Kryczek, I., Brumlik, M.J., Daniel, B.J., Coukos, G., Zou, W., Curiel, T.J. 2009. Altering regulatory T cell function in cancer immunotherapy: A novel means to boost efficacy. Book chapter in Frontiers in Bioscience, Vol (14): 1761-70
- Barnett BG, Rüter J, Kryczek I, Brumlik MJ, Cheng PJ, Daniel BJ, Coukos G, Zou W, Curiel TJ, Brumlik M. Regulatory T cells: a new frontier in cancer immunotherapy. Adv Exp Med Biol 2008 Jan;622:255-260.
- Brumlik, M. J., Daniel, B.J., Waehler, R., Curiel, D.T., Giles, F.J., Curiel, T.J..(2008). "Trends in immunoconjugate and ligand-receptor based targeting development for cancer therapy." Expert Opin Drug Deliv 5(1): 87-103.
- Wei, S., Daniel, B.J., Brumlik, M. J., Burow, M. E., Zou, W., Khan, I. A., Wadsworth, S., Siekierka, J., and Curiel. T. J., 2007. Drugs Designed To Inhibit Human p38 Mitogen-Activated Protein Kinase Activation Treat Toxoplasma gondii and Encephalitozoon cuniculi Infection. Antimicrob Agents Chemother 51:4324-4328.