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HSC to host inaugural San Antonio Vaccine Symposium

Posted: Tuesday, October 16, 2012 · Volume: XLV · Issue: 21

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Guangming Zhong, M.D., Ph.D., (left) professor of microbiology and immunology at the UT Health Science Center, and Bernard Arulanandam, Ph.D., professor of biology at UTSA and adjunct professor of microbiology and immunology at the UT Health Science Center, are two of the four co-directors of the San Antonio Vaccine Symposium.
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Guangming Zhong, M.D., Ph.D., (left) professor of microbiology and immunology at the UT Health Science Center, and Bernard Arulanandam, Ph.D., professor of biology at UTSA and adjunct professor of microbiology and immunology at the UT Health Science Center, are two of the four co-directors of the San Antonio Vaccine Symposium. clear graphic

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Contact: Will Sansom, 210-567-2579

SAN ANTONIO (Oct. 11, 2012) — The inaugural San Antonio Vaccine Symposium, titled “Vaccine Antigen Discovery and Vaccine-Induced Immunity,” is scheduled for 8 a.m. to 5:30 p.m. Friday, Nov. 16, at the Greehey Children’s Cancer Research Institute of The University of Texas Health Science Center San Antonio. The Greehey CCRI is located at 8403 Floyd Curl Dr.

The symposium is presented by the San Antonio Vaccine Development (SAVE) Center, which is marshaling the vaccine research resources of four San Antonio institutions: the UT Health Science Center, The University of Texas at San Antonio (UTSA), Texas Biomedical Research Institute and Southwest Research Institute. These partners and BioMed SA, which promotes San Antonio’s biomedical assets, announced the SAVE Center’s founding at a press conference this spring at San Antonio City Hall.

Keynote speakers
Two leading vaccine researchers who are members of the National Academy of Sciences will deliver invited keynote speeches. At 9 a.m. Nov. 16, Roy Curtiss III, Ph.D., of the Biodesign Institute at Arizona State University, will discuss “Salmonella-vectored vaccines from infectious diseases to cancer.” At 2 p.m., Rafi Ahmed, Ph.D., of the Emory Vaccine Center at Emory University, will discuss “T-cell memory and exhaustion.”

Co-scientific directors
Scientists of the SAVE institutions will have the chance to present their work in oral sessions that follow the keynote addresses. “It’s a very exciting program. These visiting scientists are much acclaimed in their fields — both are prominent in the field of vaccine discovery,” said Bernard Arulanandam, Ph.D., co-scientific director of the symposium. He is professor of biology at UTSA and adjunct professor of microbiology and immunology at the UT Health Science Center.

The other co-scientific directors are Guangming Zhong, M.D., Ph.D., professor of microbiology and immunology in the School of Medicine at the UT Health Science Center; Jean Patterson, Ph.D., scientist and chair of virology and immunology at the Texas Biomedical Research Institute; and Michael MacNaughton, Ph.D., vice president of chemistry and chemical engineering, at Southwest Research Institute.

Salmonella vectors
Dr. Curtiss will speak about delivering vaccine antigens through the use of Salmonella vectors (or carriers). Salmonella are microscopic bacteria that represent the most frequently reported cause of foodborne illness. His laboratory is interested in using microbial genetic engineering to address problems of global concern.

Antigens are substances such as bacteria, fungi or pollen that stimulate the immune system to produce antibodies. An antibody is a protein produced by the immune defenses when the harmful antigen is recognized.

Viruses and the immune response
Dr. Ahmed is an internationally recognized expert on the immune response to viruses. “Dr. Ahmed studies how responses to an antigen are maintained or remembered, which is significant since the purpose of vaccination is to induce immunological memory,” Dr. Zhong said.

Annually the SAVE symposium will enable faculty and graduate students to learn about vaccine research from infectious disease researchers around the world, Dr. Zhong said. The students will in turn have a platform to share their research with these global experts.

The oral presentations and dozens of poster presentations will “showcase San Antonio and the vaccine development work at all four SAVE institutions,” Dr. Arulanandam said. “In our own backyard, we have very promising investigators.”

Health Science Center researchers contribute to vaccine development
Francisco González-Scarano, M.D., dean of the School of Medicine and vice president for medical affairs at the Health Science Center, said the institution is proud to host the inaugural SAVE symposium. “The development of effective vaccines against infectious diseases such as AIDS, malaria and Lyme disease is key to improving human health as well as that of domesticated and agricultural animals,” he said. “The UT Health Science Center, in collaboration with the SAVE partner institutions, will contribute new understandings to alleviate the suffering caused by infectious diseases and other conditions that may be responsive to vaccination.”

Kenneth Trevett, J.D., president and chief executive officer of the Texas Biomedical Research Institute, is serving his second term as chair of the Executive Committee of BioMed SA. He said: “From diabetes to heart disease, from neuroscience to aging, from infectious diseases to mental illnesses, and many others, we are pursuing as a community new diagnostics, novel therapies and more effective vaccine strategies. The annual symposium we are launching on Nov. 16 epitomizes this quest.”

San Antonio Mayor Julián Castro said: "This symposium, and the top-flight research talent it is attracting, highlights the strength and vibrancy of San Antonio's biomedical sector.”

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The University of Texas Health Science Center at San Antonio, one of the country’s leading health sciences universities, ranks in the top 3 percent of all institutions worldwide receiving federal funding. Research and other sponsored program activity totaled $231 million in fiscal year 2011. The university’s schools of medicine, nursing, dentistry, health professions and graduate biomedical sciences have produced more than 28,000 graduates. The $739.6 million operating budget supports eight campuses in San Antonio, Laredo, Harlingen and Edinburg. For more information on the many ways “We make lives better®,” visit www.uthscsa.edu.

 
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