Department of Cellular and Structural Biology

CSB Faculty Research Interests

 

Bai, Yidong, Ph.D. Mitochondrial genetics, aging, cancer and mitochondrial medicine.

 

Bandyopadhyay, Abhik, Ph.D. Mammary stem cell biology and generation of breast cancer stem cells, Aging and breast cancer, Pre-clinical assessment of targeted molecular therapeutics.

 

Bishop, Alex, Ph.D. Systems biology and homologous recombination in carcinogenesis, DNA repair, functional genomics, genetic and environmental interactions, aging, carcinogenesis, animal models.

 

Dong, Lily Q., Ph.D. Obesity and Type 2 Diabetes.

 

Habib, Samy, M.S., Ph.D. Role of diabetes in development of cancer, molecular mechanisms of the DNA damage and repair in diabetes and cancer, Role of Tuberin/mTOR pathways in regulation of cell proliferation, cell hypertrophy and cell apoptosis.

 

Kokovay, Erzsebet, Ph.D. Adult neural stem cells and neurogenesis.

 

Kraig, Ellen, Ph.D. Aging, immunity, autoimmunity.

 

Larsen, Pamela L., Ph.D. Development and aging in C. elegans. Molecular genetics, expression analysis, functional genomics, genetic and environmental interactions and C. elegans physiology.

 

Leach, Robin J., Ph.D. Genetics of complex diseases. Development and validation of biomarkers for cancer.

 

Lechleiter, James D., Ph.D. Molecular and cellular mechanisms of protection during ischemic stress, acute brain injury and aging.

 

Marciniak, Robert A., M.D., Ph.D. Aging, mechanisms of telomere maintenance, Werner syndrome and cell regulation.

 

Moore, Charleen M., Ph.D. Comparative cytogenetics, aging, animal models, and history of anatomy.

 

Oyajobi, Babatunde O., M.B., B.Ch., Ph.D. Bone biology and cancer-induced bone diseases.

 

Penalva, Luiz Otavio F., Ph.D. Molecular analysis of cancer, post-transcriptional regulation, RNA binding proteins, cancer genomics, alternative splicing.

 

Ran, Qitao, Ph.D. Mitochondrial dysfunction, Oxidative stress, Alzheimer's disease, Aging.

 

Rao, Manjeet, Ph.D. miRNA : Development and Cancer, Epigenetics and Cancer stem cell, Functional genomics, animal models.

 

Rebel, Vivienne, M.D., Ph.D. Molecular mechanisms of hematopoietic stem cell regulation, from development to old age.

 

Reiter, Russel J., Ph.D. Melatonin in free radical biology and oxidative stress, aging, antioxidants and the pineal gland.

 

Sakaguchi, Alan Y., Ph.D. Oncogenes & tumor suppressor genes, telomere binding proteins, cell aging, cell rejuvenation.

 

Sharma, Ramaswamy, Ph.D. Osteoporosis, Mesenchymal Stem Cells, Regenerative Medicine, Apoptosis, Aging.

 

Sun, LuZhe, Ph.D. Cancer biology, Signal transduction, Stem cell, Experimental therapeutics.

 

Tardif, Suzette, Ph.D. Primate models of obesity and aging. Reproductive energetics, pregnancy & lactation and maternal obesity.

 

Vogel, Kristine S., Ph.D. Signal transduction, tumorigenesis in the peripheral nervous system. Mouse models for nervous system tumors, Apoptosis in the sympathoadrenal lineage, DNA damage and repair in the peripheral nervous system, Regulation of Nf1 gene expression during development, Adapting innovative technologies for medical education in the basic sciences.

 

Walter, Christi A., Ph.D. DNA repair and mutagenesis,paternal age effect, stem cell aging, hepatocellular carcinoma, responses to mitochondrial DNA damage.

 

Wang, Pei, Ph.D. To recapitulate the pathogenesis of Pancreatic ductal adenocarcinoma (PDAC) in vitro and in vivo to identify markers and methods for early diagnosis of PDAC and to inform the development of effective therapeutic strategies. To generate insulin producing cells and liver cells from human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSC) for modeling disease and for cell replacement therapies.

 

Watts, Lora, Ph.D. Stroke, Traumatic Brain Injury, Neuroprotective mechanisms, Oxidative stressy.

 

CSB Joint Appointed Faculty Research Interests:

Bone-targeted drugs as potential treatments for multiple myeloma, experimental therapeutics, organic chemistry.
Bone metastases, prostate cancer, bladder cancer, animal models of cancer-induced bone diseases, experimental therapeutics, tumor suppressor genes.