Department of Cellular and Structural Biology

Optical Imaging Facility

 

Mission:
To make available state-of-the-art imaging technology to investigators on the UTHSCSA campus and neighboring scientific community.

 

Rationale:
High-end instrumentation for acquisition and analysis of optical data is expensive and requires continued maintenance and improvements. The necessary commitment to this technology is often difficult to maintain within individual laboratories, especially when optical imaging is not a major focus for the laboratory. Therefore, the Core Optical Imaging Facility fills a critical need of UTHSCSA investigators and neighboring scientific community by offering,

  • access to state-of-the-art technology for imaging of living cells, tissues, and animals.

  • consultation, education and assistance regarding the theory and application of optical imaging techniques.

  • technical advice on specimen preparation techniques and probe selection.

 

New developments in optical microscopy coupled with the vast array of bio-reagents available have made it possible to observe directly the dynamics of the molecular, chemical, structural and functional environment of cells at the cellular and sub-cellular level. In particular, fluorescence microscopy has become an essential tool for scientist to detect cellular components using antibodies, nucleic acid probes and fluorescent fusion proteins as markers and to observe physiological changes using fluorescent ion indicators.

 

Developments in optical microscopy coupled with the now vast array of bio-reagents available have made it possible to observe directly the dynamics of the molecular, chemical, structural and functional environment of cells at the sub-cellular level. In particular, fluorescence microscopy has become an essential tool for scientist to detect specific cellular components using antibodies, nucleic acid probes and fluorescent fusion proteins as markers and to observe physiological changes using fluorescent ion indicators.


 

Publication Acknowledgements:

The facility should be listed in the "Acknowledgements" section of any publication using data generated in the OIF as follows:
    "Images were generated in the Core Optical Imaging Facility which is supported by UTHSCSA, NIH-NCI P30 CA54174 (CTRC at UTHSCSA) and NIH-NIA P01AG19316."