Cancer has recently surpassed heart disease as the number one killer in the U.S. population under 85. The evolving technologies in molecular biology, imaging, and rational drug design and screening have lead to rapid expansion of new strategies for prevention, detection and treatment of human malignancies.
The goal of the Cancer Biology Track is to educate the next generation of cancer researchers to meet the growing demands for scientists trained in multiple facets of cancer biology.
Faculty in this track possess a broad range of expertise in cancer research including genomics/proteomics, cell signaling and receptor biology, tumor immunology, DNA repair, structural biology, viral oncogenesis, drug discovery, chemoprevention, experimental therapeutics, and clinical trials. The curriculum stresses both basic and translational research to provide the broad background in oncology needed for today's research.
Tyler J. Curiel, M.D., M.P.H., Department of Medicine
Patricia Dahia, M.D., Ph.D., Department of Medicine
James W. Freeman, Ph.D., Department of Medicine
Peter J. Hornsby, Ph.D., Department of Physiology
Addanki Pratap Kumar, Ph.D., Department of Urology
AGUIAR, Ricardo, Biochemistry - Leukemia and lymphoma, molecular basis of clinical heterogeneity.
BISHOP, Alex, C&S Biology & GCCRI - Cancer genetics and Genomics, DNA damage/Genomic instability, Animal model systems.
BOYER, Thomas, Molecular Medicine - Role of oncoproteins and tumor suppressor proteins in transcription regulation and DNA repair.
CHATTERJEE, Bandana, Molecular Medicine - Nuclear receptors and metabolic regulation; androgen receptor in prostate cancer and gene regulation.
CHEN, Shuo, Pediatric Dentistry - Androgen receptor and prostate cancer development.
CHEN, Yidong, Epidemiology & Biostatistics, GCCRI - Bioinformatics, Genomic approaches to cancer.
CURIEL, Tyler, San Antonio Cancer Institute - Cancer immunology, translational research, signal transduction, metastasis, tumor Microenvironment.
DAHIA, Patricia, C&S Biology & Hematology/Medical Oncology - Biologcal signatures, pheochromocytomas, mitochondria, hypoxia, genomics of cancer.
FREEMAN, James W. , Hematology/Medical Oncology - Cell signaling, experimental therapeutics.
GACZYNSKA, Maria, Molecular Medicine - Role of controlled proteolysis in cancer, molecular medicine.
GHOSH, Rita, Urology - Carcinogenesis mechanisms, prevention and therapy.
GHOSH-CHOUDHURY, Nandini, Pathology - Cancer growth, apoptosis, metastasis.
HASTY, Paul, Molecular Medicine - DNA damage and repair.
HINCK, Andrew, Biochemistry - TGF beta interactions, solution NMR spectroscopy.
HORNSBY, Peter, Physiology - Role of telomeres in tumorigenesis.
HU, Yanfen, Molecular Medicine - Mechanism of BRCA1 in tumor suppression.
HUANG, Tim, Molecular Medicine - Cancer epigenetics.
HUNG, Jaclyn, Pediatrics & GCCRI - Cancer stem cells, microRNA in cancer.
IVANOV, Dmitri, Biochemistry - DNA repair, macromolecular assembly, structural biology.
JIANG, Jean, Biochemistry - Cell-cell communication.
JOHNSON-PAIS, Teresa, Pediatrics - Metastasis, arrays - cancer cell biology.
KIM, Chongwoo, Biochemistry - Polychrome group, X-ray crystallography, chromatin.
KIM, Dae Joon, Pharmacology - Protein tyrosine phosphatase, carcinogenesis, UVB irradiation, DNA damage repair.
KIRMA, Nameer, OB-GYN - Women's cancer.
KUMAR, A. Pratap, Urology - Nutritional intervention of carcinogenesis.
LEACH, Robin, C&S Biology - Cancer genetic, epidemiolog, tumor suppressor genes.
LEE, Sang, Molecular Medicine - Molecular genetics of DNA damage response.
LI, Rong, Molecular Medicine - The molecular basis of breast cancer.
LIU, Feng, Pharmamcology - Signal transduction.
MARCINIAK, Robert, C&S Biology & Hematology/Medical Oncology - Cancer, telomere maintenance.
MOOBERRY, Susan, Pharmacology - Drug discovery and development.
NATARAJAN, Mohan, Otolaryngology - Head and Neck Surgery - Tumor treatment.
NICHOLSON, Bruce, Biochemistry - Structure and function of gap junctions; gap junctions as tumor suppressors.
OSMULSKI, Pawel A., Molecular Medicine - Role of controlled proteolysis in cancer, molecular medicine.
OYAJOBI, Babatunde, C&S Biology - Myeloma bone disease, breast cancer, experimental therapeutics.
PADALECKI, Susan, C&S Biology & Urology - Bone metastases, prostate cancer, bladder cancer, animal models and breast cancer.
PENALVA, Luiz, C&S Biology & GCCRI - Post-transcriptional regulation, RBPs.
PERTSEMLIDIS, Alexander, Pediatrics & GCCRI - MicroRNAs in cancer.
RAO, Manjeet, C&S Biology & GCCRI - MicroRNAs and RNA interference in cancer.
REBEL, Vivienne, C&S Biology & GCCRI - Molecular mechanisms of stem cell regulation.
SAIKUMAR, Pothana, Pathology - Oncogenes and cell death.
SHARP, Z. Dave, Molecular Medicine - Gene regulation in development; cell growth control in cancer and aging.
SLAGA, Thomas J., Pharmacology - Carcinogenesis, prevention and therapy.
SUN, LuZhe, C&S Biology - Cancer biology, signal transduction, cell cycle, cell senescence, experimental therapeutics.
TEKMAL, Rajeshwar, OB-GYN - Breast/ovary/cervical cancers, hormonal carcinogenesis/steroid hormone research.
THOMPSON, Ian M., Urology - Urologic oncology.
TOMLINSON, Gail, Pediatrics and GCCRI - Pediatric cancers and hepatoblastoma.
VADLAMUDI, Ratna K., OB-GYN - Signal transduction, nuclear receptors, coregulators, Tg/KO mouse models.
VOGEL, Kristine, C&S Biology - NFI, animal models for nervous system cancers, DNA damage/repair.
WALTER, Chris, C&S Biology - DNA repair in development, aging and cancer.
WANG, Pei, C&S Biology - Stem cell biology and pancreatic ductal adenocarcinoma.
WARGOVICH, Michael, Molecular Medicine - Cancer chemoprevention drug discovery.
YEW, P. Renee, Molecular Medicine - Cell cycle regulation in vertebrates and the role of ubiquitin-dependent proteolysis in cancer.